Much like other retinoids, tretinoin is usually not available over the counter and requires a prescription from a board-certified dermatologist. With this in mind, board-certified dermatologist Dr. Peterson Pierre, M.D., recommends asking your dermatologist about Retin-A Micro or Altreno Topical, which are topical creams that use tretinoin as the active ingredient.

“Retin-A Micro uses tretinoin as the main active ingredient in a vehicle that allows for sustained release throughout the day,” Dr. Pierre tells HelloGiggles. “The main benefits include slow delivery of the active ingredient over time while minimizing the side effects of burning, redness, stinging, and irritation. Similarly, Altreno Topical also uses tretinoin, but the vehicle contains collagen, glycerin, and hyaluronic acid, which are all designed to minimize irritation while hydrating and moisturizing the skin.”

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